A man suffered serious injuries after being involved in a collision with a lorry on the Chapel bypass on Saturday morning.
Police were called at around 7am to the crash southbound on the A6 bypass, outside the Fickle Mermaid pub.
A pedestrian, a 32-year-old man, was seriously injured but his injuries are not thought to be life threatening. He remains in a serious but "stable" condition at Manchester Royal Infirmary.
Police say an investigation is ongoing and are asking anyone who may have witnessed the crash to call the non-emergency number 101, quoting reference number 198 of 12 October.